Yes, but... there are tons of deserving animal welfare organizations in the U.S., probably quite a few in your own back yard, so to speak.
I'd rather donate locally to help animals in my own community. Even city/county-run animal shelters can use your help, whether it's a donation of old towels so animals have something softer/warmer to sleep on than old newspapers, or a bit of your time to walk a few dogs so they can get out of their cage for a bit.