If you buy a uke that comes with Aquilas standard and it has been set up, then your nut slots may be too large for many fluorocarbon strings. In that case, you can use string spacers to stabilize the thinner strings.
Even those that don't require set up (like Fleas and Flukes) may be manufactured for thicker strings. I've had to use string spacers for the C and E strings on my Flea and Fluke because I prefer Worth browns to Aquilas on those ukes. It's not a big deal, because spacers are cheap: you can find them for about a buck apiece and each one could handle several sets of strings.