I have one bari with a high D and it does make the sound a little more ukey than guitary. And does make it easier to use reentrant tab. Also, if you don’t like wound strings and want all flo.carb, reentrant tuning keeps the D string thinner. I haven’t been happy with the thickness of low D flo.carb and acrylics are even worse. My preference though is linear tuning and wound strings.