I prefer low G tuning mostly, but also like re-entrant high G too.
I have a Larrivee spruce and mahogany soprano which sounds fantastic with a low G - it already has a darkness underneath the rather bright tone, and the low G really exploits that tonal characteristic. I also have my Ohana solid spruce top with laminated mahog back and sides strung with a low G - it sounds great and helps to balance the very bright tone of the uke. The low G gives the Ohana balast, so to speak.
My Kelii koa soprano and my LoPrinzi maple and spruce sopranos are definitely re-entrant ukes - they sound beautiful with the high G and I think they would suffer with a low G.
So it depends on what music I'm playign and also on the isntrument itself. Some sopranos are wonderful with low G, so don't prejudge based on the size of the uke. It's all about the tone and how the uke resonates, in my experience.