Is there a best key to play in?

I'm new to the Uke and I'm wondering that since four strings is more limited than six, is there a best key to play in or is it just a matter of choice? I know that singing would probably be a determining factor.
Thanks for any input,
Bill

It all depends, the only way is to explore.

songchaser said:

...is there a best key to play in or is it just a matter of choice?

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if you are a newcomer, you may find some chords more difficult to finger than others, so until you're comfortable with these 'difficult' chords you may want to avoid keys that use them.

For example, if you find the D chord 2220 awkward, you may want to transpose the song to a key that doesn't use it. So if your song has G-C-D, you may find it easier to play it in C-F-G or F-Bb-C.

There are no better or worse chords, just those that may prove a little easier to learn.

As for keys - you will probably play a lot in the naturals, at least at first, and not in any of the sharps/flats keys until you have some proficiency with barred chords and making those finger-cramping, wrist-snapping patterns some keys require.

Nah, there really is no best key to play in. I think it's a matter of learning and practicing chord shapes and the key word being practice. Mind you, it's not an overnight thing nor a few months either. Now if I can do as I say. As far as singing is concerned, you'll have to find a key that suits your vocal range.