When I went from acoustic guitar to mandolin a few years ago I found the fifths chords (GDAE) quite comfortable. So, I kept every future four-string-based instrument tuned fifths, including ukes. It made transition from one to another easier and reinforced what little skill I have. I always believed that one should not be a slave to convention and that tools (including instruments) must accommodate the human, not the other way around.
...SteveZ
Ukuleles: Martin T1K (T)*, Oscar Schmidt OU28T (T8), Lanikai LU-6 (T6), RISA Solid (C), Effin UkeStart (C), Flea (S)**
Banjo-Ukes: Duke 10 (T)*, Lanikai LB6-S (S)*
Tenor Guitars: Martin TEN515, Blueridge BR-40T
Tenor Banjo: Deering Goodtime 17-Fret
Mandolin: Burgess (#7)***
Tuning: *Reentrant C CGDA. **DAEB. ***GDAE. The rest are CGDA
The inventory is always in some flux, but that's part of the fun.
Bookmarks