Excellent points, Bill1. For the solo player especially, there's no reason why we can't make those adjustments on the basis of what (to our ear) seems to bring out the best in terms of combining the "feel" and the "voice" of the specific instrument, and settling on a tuning level that "optimizes" both factors, as long as the uke is "in tune with itself". And yes, bsfloyd, I did go ahead and tinker this afternoon with the aDF#B tuning on the Flea, but it seemed a little too "taut", and some of the notes seemed a little "stifled", so I'm back in g#C#FA# (a half-step above "standard"), which feels and sounds really nice. I must confess, I might be a little addicted to the tuner, perhaps because of the sense of security it gives me!